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南方科技大学陈默团队Trends in Cell Biology综述丨AKT信号通路的“空间 ...
PI3K-AKT信号通路是细胞生物学中最核心的调控网络之一,几乎参与了所有与生长、代谢、存活和迁移相关的重要过程。自1987年发现依赖磷脂信号的AKT蛋白激酶以来,科学界对其在细胞质中的经典激活模式已研究颇多。然而,近十余年的研究表明,AKT的功能并不仅 ...
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